Stakeholders meet for final CUSP Research Cluster events to discuss the potential human health impacts of micro- and nanoplastics

CUSP cluster holds scientific conference and stakeholder meeting as projects come to an end; all five EU projects within the cluster share research results; scientists discuss future research needs on human health and micro- and nanoplastics; stakeholders share perspectives and policy questions

Microplastics early ’25 science round-up: presence in humans and health impacts

Scientists detect more micro- and nanoplastics (MNP) in the human brain than in liver and kidney, higher levels in brains of dementia patients; find MNPs obstruct blood vessels, lead to neurobehavioral abnormalities; MNPs in women’s follicular fluid associated with lower fertilization rates; maternal MNP exposure impairs fertility of female mice offspring; “bioplastic” MNPs induce male reproductive toxicity in mice

AURORA study examines cell uptake and interactions of polystyrene MNPs with hormone receptors

Researchers from the AURORA consortium publish a study testing for potential endocrine-disrupting effects of polystyrene (PS) micro- and nanoplastic (MNP) particles; finds uptake of PS-MNP particles differs per cell type; detects limited endocrine-disrupting effects in vitro; reports that PS-MNPs can affect steroidogenesis; study calls for needed additional research

Recent studies show that MNPs can negatively impact reproductive health

Studies confirm micro- and nanoplastics (MNPs) in human endometrial tissue, amniotic fluid, placentas, and feces of pregnant people; MNP presence in the endometrium is linked with recurrent miscarriages in humans, apoptosis in organoids, and reduced fertility in mice; higher MNPs exposure from seafood and bottled water consumption

What happens to micro- and nanoplastics in the body?

Study proposes a preliminary physiologically-based toxicokinetic (PBTK) model for micro- and nanoplastics (MNPs); polymer type, size, shape, surface chemistry, surface biofilms, and biocorona determine toxicokinetic rates; models for engineered nanoparticles are not appropriate due to heterogeneity of MNPs; uptake via inhalation and effects of absorbed chemicals need more investigation

AURORA project featured in public health webinar 

Webinar on human exposure and health effects of micro and nanoplastics hosted by Collaborative for Health & Environment puts a spotlight on AURORA and POLYRISK; AURORA project coordinator Roel Vermeulen speaks about progress and challenges; shares first project preliminary results; emphasizes the need for further research and standardized methods